1. indicating opposition or resistance (Freq. 1) • Syn: counter • Similar to: negative • Derivationally related forms: antagonist, antagonism 2. characterized by antagonism or antipathy (Freq. 1) - slaves antagonistic to their masters - antipathetic factions within the party • Syn: antipathetic, antipathetical • Similar to: hostile • Derivationally related forms: antipathy (for: antipathetical), antipathy (for: antipathetic), antagonism 3. arousing animosity or hostility - his antagonistic brusqueness - Europe was antagonistic to the Unites States • Ant: conciliatory • Similar to: alienating • Derivationally related forms: antagonism 4. used especially of drugs or muscles that counteract or neutralize each other's effect • Syn: incompatible • Ant: synergistic • Similar to: antacid, antiphlogistic • Derivationally related forms: antagonist, antagonism 5. incapable of harmonious association • Similar to: incompatible • Derivationally related forms: antagonism